Targets of Ribavirin
TargetName References EssentialGene? Link
5'-nucleotidase cytosolic II No
Adenosine kinase Yes
E-NPP 1 No
IMP dehydrogenase 2 Yes
Inosine-5'-monophosphate dehydrogenase 1 No
Large structural protein No
NPH I No
NPH II No
PB1 Yes
RNA-directed RNA polymerase catalytic subunit No
DNA Yes
Cytosolic purine 5'-nucleotidase No
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 No
RNA-directed RNA polymerase inhibitor No

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