Targets of amiodarone
TargetName References EssentialGene? Link
(R)-limonene 6-monooxygenase No
Albendazole monooxygenase No
Alpha-1A adrenergic receptor No
Anthrax lethal toxin endopeptidase component No
ATP-binding cassette sub-family B member 1 No
Beta-1 adrenergic receptor Yes
c-erbA-1 Yes
CYPIA1 No
CYPIA2 Yes
CYPIIC8 No
CYPIID6 No
CYPIIIA5 No
CYPIIIA7 No
Cytochrome P450 Yes
Cytochrome P450 3A4 No
Cytochrome P450 CYP3A4 No
Cytochrome P450 family 3 subfamily A polypeptide 4 No
Nuclear receptor subfamily 1 group A member 2 Yes
Potassium voltage-gated channel subfamily H member 2 No
Voltage-dependent T-type calcium channel subunit alpha-1H No
Voltage-dependent calcium channel subunit alpha-2/delta-2 Yes
voltage-gated potassium channel (KCND3) blocker No
voltage-gated potassium channel (KCNH2) blocker No
voltage-gated potassium channel (KCNQ1) blocker No
potassium inwardly-rectifying channel (KCNJ3) No
potassium inwardly-rectifying channel (KCNJ5) No
potassium inwardly-rectifying channel (KCNJ8) No
potassium inwardly-rectifying channel (KCNJ11) No
potassium inwardly-rectifying channel (KCNJ12) No
voltage-gated sodium channel blocker No
P-glycoprotein inhibitor No
alpha1-adrenergic receptor agonist No
beta1-adrenergic receptor agonist No

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