Detail for Sulfamethoxazole
Basic Information
DrugID 98
DrugName Sulfamethoxazole
DrugDetail Sulfamethoxazole (abbreviated SMZ or SMX) is a sulfonamide bacteriostatic antibiotic. It is most often used as part of a synergistic combination with trimethoprim in a 5:1 ratio in co-trimoxazole (abbreviated SMZ-TMP and SMX-TMP, or TMP-SMZ and TMP-SMX), also known under trade names such as Bactrim, Septrin, or Septra; in Eastern Europe it is marketed as Biseptol. Its primary activity is against susceptible forms of Streptococcus, Staphylococcus aureus (including MRSA), Escherichia coli, Haemophilus influenzae, and oral anaerobes. It is commonly used to treat urinary tract infections. In addition it can be used as an alternative to amoxicillin-based antibiotics to treat sinusitis. It can also be used to treat toxoplasmosis and it is the drug of choice for Pneumocystis pneumonia, which affects primarily patients with HIV.

http://en.wikipedia.org/wiki/Sulfamethoxazole

Indication For the treatment bacterial infections causing bronchitis, prostatitis and urinary tract infections.

http://www.drugbank.ca/drugs/DB01015

Structure Click to see the orginal picture.
Interaction
Drug Name PMIDLink Reference
Caspofungin Yekutiel A, Shalit I, Shadkchan Y, Osherov N. (2004) In vitro activity of caspofungin combined with sulfamethoxazole against clinical isolates of Aspergillus spp. Antimicrob Agents Chemother. 48(9):3279-83.
Target
PathWay
PathWay Name Path Picture
pathway