Detail for nitric oxide
Basic Information
DrugID 75
DrugName nitric oxide
DrugDetail Nitric oxide or Nitrogen monoxide is a chemical compound with chemical formula NO. This gas is an important signaling molecule in the body of mammals including humans and is an extremely important intermediate in the chemical industry. It is also a toxic air pollutant produced by automobile engines and power plants. Nitric oxide (NO) should not be confused with nitrous oxide (N2O), a general anaesthetic, or with nitrogen dioxide (NO2) which is another poisonous air pollutant. The nitric oxide molecule is a free radical, which is relevant to understanding its high reactivity. It reacts with the ozone in air to form nitrogen dioxide, signalled by the appearance of the reddish-brown color.

http://www.drugbank.ca/drugs/DB00435

http://en.wikipedia.org/wiki/Nitric_oxide

Indication INOmax (nitric oxide) , in conjunction with ventilatory support and other appropriate agents,is indicated for the treatment of term and near-term ( > 34 weeks) neonates with hypoxic respiratory failure associated with clinical or echocardiographic evidence of pulmonary hypertension, where it improves oxygenation and reduces the need for extracorporeal membrane oxygenation.

http://www.rxlist.com/inomax-drug/indications-dosage.htm

Structure Click to see the orginal picture.
Interaction
Drug Name PMIDLink Reference
Fluconazole McElhaney-Feser GE, Raulli RE, Cihlar RL. (1998) Synergy of nitric oxide and azoles against Candida species in vitro. Antimicrob Agents Chemother. 42(9):2342-6.
Ketoconazole McElhaney-Feser GE, Raulli RE, Cihlar RL. (1998) Synergy of nitric oxide and azoles against Candida species in vitro. Antimicrob Agents Chemother. 42(9):2342-6.
Miconazole McElhaney-Feser GE, Raulli RE, Cihlar RL. (1998) Synergy of nitric oxide and azoles against Candida species in vitro. Antimicrob Agents Chemother. 42(9):2342-6.
Target
PathWay