Detail for Latrunculin A
Basic Information
DrugID 63
DrugName Latrunculin A
DrugDetail Latrunculin A is an actin binding macrolide purified from the red sea sponge Latrunculia magnifica. It is under investigation for the treatment of cancer. It disrupts actin polymerization, prevents mitotic spindle formation and thus cell replication.

Structure Click to see the orginal picture.
Drug Name PMIDLink Reference
Fluconazole Jansen G., Lee A.Y., Epp E., Fredette A., Surprenant J., Harcus D., Scott M., Tan E., Nishimura T., Whiteway M., Hallett M., Thomas D.Y. (2009) Chemogenomic profiling predicts antifungal synergies. Molecular Systems Biology 5. DOI: 10.1038/msb.2009.95.