Detail for doxycycline
Basic Information
DrugID 42
DrugName doxycycline
DrugDetail Doxycycline INN is a member of the tetracycline antibiotics group, and is commonly used to treat a variety of infections. Doxycycline is a semisynthetic tetracycline invented and clinically developed in the early 1960s by Pfizer Inc. and marketed under the brand name Vibramycin. Vibramycin received U.S. Food and Drug Administration approval in 1967,[citation needed] becoming Pfizer's first once-a-day, broad-spectrum antibiotic. Other brand names include Monodox, Microdox, Periostat, Vibra-Tabs, Oracea, Doryx, Vibrox, Adoxa, Doxyhexal, Doxylin, Doxoral,Doxy-1 and Atridox (topical doxycycline hyclate for periodontitis).

http://en.wikipedia.org/wiki/Doxycycline

Indication Doxycycline is indicated for use in respiratory tract infections caused by Mycoplasma pneumoniae, Haemophilus influenzae, Streptococcus pneumoniae, Legionella spp., or Klebsiella spp. It is also used for prophylaxis of malaria. Doxycycline is indicated for a variety of bacterial infections, from Mycobacterium fortuitum and M. marinum, to susceptible E. coli and Brucella spp. It can be used as an alternative to treating plague, tetanus, Campylobacter fetus

http://www.drugbank.ca/drugs/DB00254

Structure Click to see the orginal picture.
Interaction
Drug Name PMIDLink Reference
Fluconazole Miceli MH, Bernardo SM, Lee SA. (2009) In vitro analyses of the combination of high-dose doxycycline and antifungal agents against Candida albicans biofilms. Int J Antimicrob Agents. 34(4):326-32.
Target
PathWay
PathWay Name Path Picture
pathway