Detail for Cilofungin
Basic Information
DrugID 26
DrugName Cilofungin
DrugDetail Cilofungin is the first clinically applied member of the Echinocandin family of antifungal drug. It was derived from a fungus in the genus Aspergillus. It accomplishes this by interfering with an invading fungus' ability to synthesize the cell wall (specifically, it inhibits the conversion of lanosterol to ergosterol).

http://en.wikipedia.org/wiki/Cilofungin

Indication Cilofungin is the Echinocandin family of antifungal drug.

http://en.wikipedia.org/wiki/Cilofungin

Structure Click to see the orginal picture.
Interaction
Drug Name PMIDLink Reference
Amphotericin B Hanson LH, Perlman AM, Clemons KV, Stevens DA. (1991) Synergy between cilofungin and amphotericin B in a murine model of candidiasis. Antimicrob Agents Chemother. 35(7):1334-7.
Amphotericin B Sugar AM, Goldani LZ, Picard M. (1991) Treatment of murine invasive candidiasis with amphotericin B and cilofungin: evidence for enhanced activity with combination therapy. Antimicrob Agents Chemother. 35(10):2128-30.
Target
TargetName References EssentialGene? Link
beta-1,3-glucan synthesis inhibitor No
PathWay
PathWay Name Path Picture
pathway