Detail for acetic acid
Basic Information
DrugID 2
DrugName acetic acid
DrugDetail Acetic Acid is a product of the oxidation of ethanol and of the destructive distillation of wood. It is used locally, occasionally internally, as a counterirritant and also as a reagent. (Stedman, 26th ed) Acetic acid otic (for the ear) is an antibiotic that treats infections caused by bacteria or fungus.

http://www.drugbank.ca/drugs/DB03166

Indication For the treatment of superficial infections of the external auditory canal caused by organisms susceptible to the action of the antimicrobial.

http://www.rxlist.com/acetic-acid-drug/indications-dosage.htm

http://www.drugs.com/pro/acetic-acid.html

Structure Click to see the orginal picture.
Interaction
Drug Name PMIDLink Reference
Fluconazole Moosa MY, Sobel JD, Elhalis H, Du W, Akins RA. (2004) Fungicidal activity of fluconazole against Candida albicans in a synthetic vagina-simulative medium. Antimicrob Agents Chemother. 48(1):161-7.
Target
TargetName References EssentialGene? Link
(1->3,1->4)-beta-glucanase isoenzyme EII No
(S)-2-haloacid dehalogenase No
1,3,4,6-tetrachloro-1,4-cyclohexadiene hydrolase No
1,4-alpha-D-glucan maltohydrolase No
1,4-beta-N-acetylmuramidase C Yes
1-deoxy-D-xylulose 5-phosphate reductoisomerase Yes
1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1 No
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase Yes
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Yes
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Yes
2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolase?(EMBL BAA12150.1) No
33 kDa chaperonin No
4-aminobutyrate aminotransferase, mitochondrial No
4-cresol dehydrogenase [hydroxylating] flavoprotein subunit No
4-hydroxyphenylpyruvate dioxygenase No
5'-nucleotidase surE1 No
6,7-dimethyl-8-ribityllumazine synthase Yes
Acetate kinase Yes
Acetylcholinesterase Yes
Acetylglutamate kinase No
Acyl-[acyl-carrier-protein] desaturase, chloroplastic No
Adenosine kinase Yes
Adenylosuccinate synthetase isozyme 1 No
Adsorption protein P2 No
Alcohol dehydrogenase No
Alcohol dehydrogenase class 4 mu/sigma chain No
Aldo-keto reductase family 1 member C2 No
Aldo-keto reductase family 1 member C3 No
Alkaline cellulase No
Alpha-1-purothionin No
Alpha-like toxin BmK-M4 No
Alpha-N-acetylgalactosaminidase No
Alpha-xylosidase No
Aminoglycoside 3'-phosphotransferase No
Ammonia channel No
Angiotensin-converting enzyme Yes
Anthranilate phosphoribosyltransferase 2 No
Anthrax toxin receptor 2 No
Antifungal peptide 2 No
Apocytochrome f No
Arabinose operon regulatory protein No
Archaeal histone A No
Arsenical resistance operon repressor, putative?(EMBL AAB91060.1) No
Aspartate ammonia-lyase No
Beta-1,4-mannanase?(EMBL AAC44232.1) No
Beta-gal Yes
Beta-galactosidase Yes
Beta-lactamase No
Beta-lactamase IMP-1 No
Beta-lactamase VIM-2?(EMBL AAK19121.1) No
BH3498 protein?(EMBL BAB07217.1) No
Bifunctional polymyxin resistance protein arnA No
Bifunctional protein putA No
Branched-chain-amino-acid aminotransferase, mitochondrial No
C-1-tetrahydrofolate synthase, cytoplasmic No
CA Y No
CA-II No
Calmodulin Yes
Camphor 5-monooxygenase No
Carbonate dehydratase Yes
Carbonic anhydrase 12 No
Catalase No
CA-XIV Yes
C-C motif chemokine 5 No
CCA-adding enzyme No
Cell cycle arrest protein BUB3 No
Cephalosporin C deacetylase No
Chemosensory protein?(EMBL AAF71289.1) No
Chemotaxis protein CheA No
Chemotaxis protein CheY No
Chymotrypsin-like elastase family member 1 No
Clavaminate synthase 1 No
Complement decay-accelerating factor No
Concanavalin-A No
Copper-containing nitrite reductase No
Creatine kinase B-type No
C-terminal-binding protein 1 No
Cyclomaltodextrin glucanotransferase No
Cyclopropane mycolic acid synthase 1 No
Cysteine desulfurase Yes
Cystic fibrosis transmembrane conductance regulator Yes
Cytochrome c-552 No
Cytosine aminohydrolase No
D-alanine aminotransferase No
D-aminoacylase?(EMBL AAK15530.1) No
Dehydrogenase/reductase SDR family member 11 No
Deoxyuridine 5'-triphosphate nucleotidohydrolase Yes
Dephospho-CoA kinase Yes
Dihydrodipicolinate reductase Yes
Dihydroorotate dehydrogenase (quinone), mitochondrial No
Dihydroorotate dehydrogenase A (fumarate) No
DNA primase Yes
DNA repair protein XRCC4 No
DNA-binding response regulator?(EMBL AAK75333.1) No
DNA-directed RNA polymerase subunit L No
dTMP kinase Yes
Endo-1,4-beta-xylanase A No
Endo-1,4-beta-xylanase Y No
Endoglucanase 5A No
Endoglucanase G No
Endoglucanase?(EMBL AAM77714.2) No
Endoribonuclease EndoA No
Enhancing lycopene biosynthesis protein 2 No
ER-beta Yes
Exoglucanase-6A No
Exonuclease Yes
Extracellular matrix-binding protein ebh No
Ferredoxin-dependent glutamate synthase 2 No
Fiber protein?(EMBL CAA64230.1) No
Folate-binding protein Yes
Fumarate reductase flavoprotein subunit No
Fumarylacetoacetase Yes
G/T mismatches repair enzyme No
Gag-Pol polyprotein No
Galactose oxidase No
Ganglioside GM2 activator No
GDP-mannose 6-dehydrogenase No
General odorant-binding protein lush No
Genome polyprotein No
GFOR No
GFP-like non-fluorescent chromoprotein FP595 No
Glandular kallikrein Yes
Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] Yes
Glutamate decarboxylase alpha No
Glutamate decarboxylase beta No
Glutamate receptor 2 Yes
Glycosyl transferase?(EMBL AAB48385.1) No
Haloalkane dehalogenase No
Heat shock factor protein Yes
Heat shock protein HSP 90-alpha No
Hermaphrodization of XO animals protein 1 No
High frequency lysogenization protein hflD No
Histone-lysine N-methyltransferase, H3 lysine-79 specific No
HMBS No
Holliday junction ATP-dependent DNA helicase RuvB No
Hydroxyacid oxidase 2 No
Hydroxyacylglutathione hydrolase 2, mitochondrial No
Hydroxyacylglutathione hydrolase, mitochondrial No
Hydroxylamine reductase No
Hydroxynitrilase No
Hypoxanthine-guanine phosphoribosyltransferase?(EMBL AAM25533.1) No
Ig kappa chain V-II region 26-10 No
Imidazole glycerol phosphate synthase subunit hisH No
Imidazoleglycerol-phosphate dehydratase No
Indole-3-glycerol phosphate synthase?(PDB 1VC4) No
Interferon-stimulated gene 20 kDa protein No
Isobutyryl-CoA dehydrogenase, mitochondrial No
Kallikrein-1 No
KHG/KDPG aldolase No
Kinesin-1 heavy chain No
Lectin No
Leghemoglobin A No
Leghemoglobin-2 No
Leukotriene A-4 hydrolase No
Lipoprotein mxiM No
L-lactate dehydrogenase A chain No
Macrophage metalloelastase Yes
Magnesium-dependent phosphatase 1 No
Malonyl CoA:acyl carrier protein malonyltransferase?(EMBL CAA60199.1) No
Meso-diaminopimelate D-dehydrogenase No
Methionine aminopeptidase Yes
Methionine synthase Yes
Molybdenum cofactor biosynthesis protein B No
Molybdopterin-guanine dinucleotide biosynthesis protein A No
MutT/nudix family protein?EMBL AAL64824.1 No
NADPH-ferredoxin reductase fprA No
Neural hemoglobin No
Nine-heme cytochrome c No
Nitric oxide synthase, brain Yes
Nitric oxide synthase, endothelial Yes
Non-secretory ribonuclease No
Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein?(EMBL AAD36298.1) No
Outer membrane protein yopM No
Oxygen-insensitive NAD(P)H nitroreductase No
Parvalbumin alpha No
Penicillopepsin No
Peroxidase C1A No
Phenazine biosynthesis protein phzF No
Phosphatidylethanolamine-binding protein 1 No
Phosphoenolpyruvate carboxykinase [ATP] No
Phosphoenolpyruvate carboxykinase, cytosolic [GTP] Yes
Phosphoglycolate phosphatase No
Phospholipase A2 isoform 2?(EMBL AAR19228.1) No
Phospholipase A2 isoform 3 No
Phospholipase A2 VRV-PL-VIIIa No
Phospholipase A2, major isoenzyme No
Phosphoribosylglycinamide formyltransferase 2 No
Phosphoserine phosphatase No
PhzG?(EMBL AAC64493.2) No
Plasminogen activator inhibitor 1 No
Platelet-activating factor acetylhydrolase IB subunit alpha Yes
Platelet-activating factor acetylhydrolase IB subunit gamma Yes
Polygalacturonase inhibitor 2 No
Protein CrcA No
Protein-tyrosine-phosphatase?(EMBL AAD45611.1) No
Proto-oncogene tyrosine-protein kinase Fyn Yes
Proto-oncogene tyrosine-protein kinase LCK No
Purothionin A-1 No
Putative HMP/thiamine-binding protein ykoF No
Putative mannose-6-phosphate isomerase yvyI No
Putative ribosome biogenesis GTPase RsgA No
Putative snRNP Sm-like protein No
Putative uncharacterized protein (TTHA1528?EMBL BAD71351.1) No
Putative uncharacterized protein PH0642?(EMBL BAA29733.1) No
Putative uncharacterized protein?(EMBL AAD36525.1) No
Putative uncharacterized protein?(EMBL AAK22477.1) No
Putative uncharacterized protein?(EMBL AAK28597.1) No
Putative uncharacterized protein?(EMBL AAL62991.1) No
Putative uncharacterized protein?(EMBL CAB02407.1) No
Quinone oxidoreductase No
RdmB?(EMBL AAA83421.1) No
Red fluorescent protein eqFP611 No
Resistin No
Reticulon-4 receptor No
Ribonuclease pancreatic No
Ribonucleoside-diphosphate reductase subunit M2 Yes
Ribosome-recycling factor No
Ricin No
rRNA adenine N-6-methyltransferase No
RutC family protein yabJ No
Serum amyloid P-component No
SH3 domain-binding glutamic acid-rich-like protein 3 No
Shikimate dehydrogenase No
Signal recognition particle protein Yes
Similar to host factor-1?(EMBL BAB57467.1) No
Siroheme synthase Yes
Small nuclear ribonucleoprotein homolog (Sm-like)?(EMBL AAL63028.1) No
Small nuclear ribonucleoprotein homolog (Sm-like)?(EMBL AAL63962.1) No
SnRNP, putative?(EMBL AAB90874.1) No
Soluble calcium-activated nucleotidase 1 No
Soluble lytic murein transglycosylase No
Spliceosome RNA helicase Ddx39b No
Staphopain A No
Streptavidin No
Sugar phosphatase SupH No
Sulfate adenylyltransferase No
Superoxide dismutase [Cu-Zn] Yes
Superoxide dismutase [Fe] No
Superoxide dismutase [Ni] No
Synaptotagmin-1 Yes
Thioredoxin Yes
Thiosulfate sulfurtransferase No
Thiosulfate sulfurtransferase glpE No
Toxin BmKaIT1 No
Transthyretin No
Trigger factor No
Triosephosphate isomerase Yes
Trypsin No
Tubulin-specific chaperone A No
Type-2 restriction enzyme BglII No
Tyrosine-protein kinase receptor TYRO3 Yes
Tyrosine-protein phosphatase non-receptor type 1 Yes
UDP-N-acetylglucosamine 2-epimerase?RuleBase RU003513 No
Uncharacterized mitochondrial hydrolase FMP41 No
Uncharacterized protein yesE No
Uncharacterized protein yesU No
Uncharacterized protein YML079W No
UPF0079 ATP-binding protein HI_0065 No
UPF0098 protein ybhB No
UPF0124 protein yfiH No
Uracil phosphoribosyltransferase Yes
Uridine phosphorylase No
Vanillyl-alcohol oxidase No
Vimentin No
Volvatoxin A2?(EMBL AAQ92757.1) No
Xaa-Pro aminopeptidase No
Xanthine dehydrogenase/oxidase Yes
PathWay