Detail for Bupivacaine
Basic Information
DrugID 18
DrugName Bupivacaine
DrugDetail Bupivacaine is a local anaesthetic drug belonging to the amino amide group.Bupivacaine is indicated for local anesthesia including infiltration, nerve block, epidural, and intrathecal anesthesia. Bupivacaine often is administered by epidural injection before total hip arthroplasty. It also is commonly injected to surgical wound sites to reduce pain for up to 20 hours after the surgery. Sometimes, bupivacaine is co-administered with epinephrine to prolong the duration of its action, fentanyl for epidural analgesia, or glucose.

http://en.wikipedia.org/wiki/Bupivacaine

Indication For the production of local or regional anesthesia or analgesia for surgery, for oral surgery procedures, for diagnostic and therapeutic procedures, and for obstetrical procedures.

http://www.drugbank.ca/drugs/DB00297

Structure Click to see the orginal picture.
Interaction
Drug Name PMIDLink Reference
Amphotericin B Rodrigues AG, Araujo R, Pina-Vaz C. (2006) Interaction of local anaesthetics with other antifungal agents against pathogenic Aspergillus. Int J Antimicrob Agents. 27(4):339-43.
Caspofungin Rodrigues AG, Araujo R, Pina-Vaz C. (2006) Interaction of local anaesthetics with other antifungal agents against pathogenic Aspergillus. Int J Antimicrob Agents. 27(4):339-43.
Itraconazole Rodrigues AG, Araujo R, Pina-Vaz C. (2006) Interaction of local anaesthetics with other antifungal agents against pathogenic Aspergillus. Int J Antimicrob Agents. 27(4):339-43.
nikkomycin Z Hector RF, Schaller K. (1992) Positive interaction of nikkomycins and azoles against Candida albicans in vitro and in vivo. Antimicrob Agents Chemother. 36(6):1284-9.
Target
PathWay
PathWay Name Path Picture
pathway